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1.
Prensa méd. argent ; 108(5): 290-292, 20220000. graf, tab
Article in English | LILACS, BINACIS | ID: biblio-1392738

ABSTRACT

Objetivos: evaluar la incidencia de la desnutrición global en el Departamento de externos del Hospital de Enseñanza de Kerbala y los factores asociados que incluyen el sexo de los pacientes, el empleo paterno y el tipo de alimentación. Métodos: mediante el uso de M.U.A.C, que es una prueba antropométrica de detección simple para la desnutrición. El estudio transversal aleatorizado de 1000 niños entre los 6-59 meses había tomado en el estudio. Del Departamento de Outpatiente del Hospital de Enseñanza de Kerbala. Datos registrados con respecto al género de pacientes, empleo paternal y tipo de alimentación en aquellos menos de 2 años. Pacientes viejos. Resultados: La incidencia general de desnutrición global fue del 6,9% en el Departamento de Overpatismo del Hospital de Enseñanza de Kerbala. Existe una fuerte asociación entre la desnutrición y el tipo de alimentación durante los primeros 2 años y hubo alguna asociación entre el empleo de padres y la desnutrición.


Objectives: To evaluate the incidence of global malnutrition in outpatient department of Kerbala teaching hospital and the associated factors which include sex of patients, paternal employment and type of feeding. Methods: By using M.U.A.C which is simple screening anthropometric test for malnutrition. Randomized Cross sectional study of 1000 child between the age of 6-59 months had taken in the study. From outpatient department of Kerbala teaching hospital. Data recorded regarding gender of patients, paternal employment and type of feeding in those less than 2 yrs. old patients. Results: Overall incidence of global malnutrition was 6.9% in outpatient department of Kerbala teaching hospital. There is strong association between malnutrition and type of feeding during first 2 years and there was some association between employment of parents and malnutrition.


Subject(s)
Humans , Infant , Child, Preschool , Socioeconomic Factors , Anthropometry , Global Health/statistics & numerical data , Malnutrition/etiology
2.
Arq. gastroenterol ; 58(2): 246-252, Apr.-June 2021. tab
Article in English | LILACS | ID: biblio-1285328

ABSTRACT

ABSTRACT BACKGROUND: Cirrhosis is a chronic and progressive liver disease that occurs from prolonged hepatocellular injury. Malnutrition causes complications in cirrhosis patients that worsen the condition to liver failure. Both are closely linked and increase the chances of morbidity and mortality. Regular nutritional screening and monitoring is prime concern for such patients including comprehensive dietary history, laboratory tests, and evaluation of muscle loss and strength capabilities to determine the degree of frailty. For efficient assessment of liver cirrhosis patients Subjective Global Assessment has been used worldwide. The nutritional objectives for such individuals should be to regain liver functions, to prevent complications associated, and to overcome nutritional deficiencies causing malnutrition. METHODS: We conducted a literature review using PubMed, Google Scholar and Science Direct for this purpose, a total of 130 articles were reviewed out of which 80 (from the past 5 years) including originally published research, review articles and abstracts were also included. Exclusion criteria of the selected studies was year of publication, irrelevancy and animal studies based on the purpose of current study. The aim of this study was to check nutritional management in patients having complications of liver cirrhosis. RESULTS: According to the guidelines, for the conservation of normal nutritional status of the malnourished patients', energy should be provided 35 kcal/kg/day while to prevent hypoalbuminemia and maintain the protein stores in the body, 1.5 g/kg/day protein has been recommended. Carbohydrates and fats for cirrhosis patients are recommended 50% to 60% and 10% to 20% of the total dietary intake respectively. CONCLUSION: Initial identification and prevention of malnutrition have the probability to lead to better health outcomes, prevention of complications of the disease, and improving quality of life.


RESUMO CONTEXTO: A cirrose hepática é uma doença crônica e progressiva que ocorre por lesão hepatocelular prolongada. A desnutrição causa complicações em pacientes com cirrose que pioram a condição para insuficiência hepática. A cirrose e a desnutrição estão intimamente ligadas e aumentam as chances de morbidade e mortalidade. O rastreamento e monitoramento nutricional regulares são as principais preocupações para esses pacientes, incluindo histórico alimentar abrangente, testes laboratoriais e avaliação de capacidades de perda muscular e força para determinar o grau de fragilidade. Para uma avaliação eficiente de pacientes com cirrose hepática, a Avaliação Global Subjetiva tem sido usada em todo o mundo. Os objetivos nutricionais desses indivíduos devem ser recuperar as funções hepáticas, prevenir complicações associadas e superar deficiências nutricionais que causam desnutrição. MÉTODOS: Realizada uma revisão de literatura usando PubMed, Google Scholar e Science Direct para este fim, e um total de 130 artigos foram revisados dos quais 80 (dos últimos 5 anos), incluindo pesquisas publicadas originalmente. Artigos de revisão e resumos também foram incluídos. Os critérios de exclusão dos estudos selecionados foram ano de publicação, irrelevância e estudos em animais com base na finalidade do estudo atual. O objetivo deste estudo foi verificar o manejo nutricional em pacientes com complicações da cirrose hepática. RESULTADOS: De acordo com as diretrizes, para a conservação do estado nutricional normal dos pacientes desnutridos, a energia deve ser fornecida 35 kcal/kg/dia, enquanto para prevenir hipoalbuminemia e manter os estoques de proteínas no corpo, 1,5 g/kg/dia de proteína foi recomendada. Carboidratos e gorduras para pacientes com cirrose são recomendados de 50% a 60% e 10% a 20% da ingestão alimentar total, respectivamente. CONCLUSÃO: A identificação inicial e a prevenção da desnutrição têm a probabilidade de levar a melhores desfechos de saúde, prevenção de complicações da doença e melhoria da qualidade de vida.


Subject(s)
Humans , Nutrition Assessment , Malnutrition/etiology , Malnutrition/prevention & control , Quality of Life , Nutritional Status , Liver Cirrhosis/complications
3.
Prensa méd. argent ; 107(4): 240-244, 20210000. tab, graf
Article in English | LILACS, BINACIS | ID: biblio-1359454

ABSTRACT

Antecedentes: La desnutrición es un importante problema de salud en el grupo de edad de pediatría que contribuye a aumentar la mortalidad y morbilidad de los pacientes ingresados. Pacientes y método: Estudio descriptivo, aleatorizado, transversal de 2965 casos entre 6 y 60 meses de los cuales 500 casos tenían desnutrición desde el 15 de noviembre de 2019 al 31 de enero de 2020, datos hospitalarios para evaluar la incidencia de desnutrición aguda severa y desnutrición aguda moderada y leve. Desnutrición y su relación con algunos factores sociodemográficos (trabajo paterno, peso al nacer, tipo de alimentación, edad, sexo). Resultados: la incidencia de desnutrición aguda severa es 1%, la incidencia de desnutrición aguda moderada es 10% y desnutrición leve 27% de la muestra de pacientes tomada 469 pacientes existe una fuerte relación de todos los grados de desnutrición con la edad paterna y bajo nacimiento peso con alguna relación con el tipo de alimentación. Conclusiones: si bien la incidencia de desnutrición aguda severa ha disminuido en los últimos años en el hospital universitario de Karbala, existe un marcado aumento en la incidencia de desnutrición aguda moderada y desnutrición leve con su impacto en la salud pediátrica general en cuanto a morbilidad y mortalidad se deben tomar esfuerzos para manejar la desnutrición aguda moderada y desnutrición leve ofreciendo asesoramiento y apoyo nutricional especialmente en personas que no son Empleadores gubernamentales.


Background: Malnutrition is a major health problem in pediatrics age group contribute to increase mortality and morbidity of admitted patients. Patients and method: A descriptive randomized cross sectional study of 2965 cases between 6 -60 months from which 500 cases had malnutrition from15th of November 2019 to 31st of January 2020 hospital-based data to evaluate incidence of sever acute malnutrition and moderate acute malnutrition and mild malnutrition and its relation to some sociodemographic factors (paternal job, birth weight, type of feeding, age, sex). Results: the incidence of severe acute Malnutrition is 1%, the incidence of moderate acute malnutrition is 10% and mild malnutrition 27% from the sample of patients taken 469 patients there is a strong relationship of all degree of malnutrition to paternal age and low birth weight with some relation to type of feeding. Conclusions: while the incidence of severe acute malnutrition has been decreased last years In Karbala teaching hospital, there is marked increase in incidence of moderate acute malnutrition and mild malnutrition with their impact on general pediatric health regarding morbidity and mortality efforts should be taken to manage the moderate acute malnutrition and mild malnutrition by offering nutritional advice and support especially in people who are not governmental Employer.


Subject(s)
Humans , Infant , Child, Preschool , Socioeconomic Factors , Demography/statistics & numerical data , Epidemiology, Descriptive , Incidence , Cross-Sectional Studies/statistics & numerical data , Morbidity , Malnutrition/etiology , Malnutrition/mortality
4.
J. health med. sci. (Print) ; 7(1): 25-30, ene.-mar. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1380355

ABSTRACT

Las úlceras por presión son lesiones de la piel y/o del tejido subyacente. El soporte nutricional adecuado constituye parte del tratamiento de estas lesiones. El objetivo de este reporte es demostrar la eficacia del soporte nutricional como factor coadyuvante en la recuperación de éstas. Paciente masculino de 29 años de edad que ingresó al hospital con diagnóstico de neuroinfección. Durante su estadía desarrolló una úlcera en la región sacra. Fue tratado con nutrición enteral por sonda nasoentérica que incluyó dieta y soporte nutricional hiperproteicos enriquecido con glutamina y arginina; posteriormente se brindó colágeno hidrolizado. A los 36 días tras la aparición de la úlcera, ésta es recuperada. Luego de 4 meses, el paciente fue dado de alta. La intervención nutricional fue crucial en la recuperación de la úlcera. Se enfatiza la necesidad de prevenirlas a través de un monitoreo oportuno y adecuado.


Pressure ulcers are injuries to the skin and / or the underlying tissue. Opportune nutritional support is part of the treatment of these injuries. This report aims to demonstrate the efficacy of nutritional support as a contributing factor in this ulcer recovery. A 29-year-old male patient was admitted to the hospital with a diagnosis of neuroinfection. During his stay, he developed a pressure ulcer in the sacral region. He was treated with enteral nutrition via a nasoenteric tube that included a hyperprotein diet and nutritional support enriched with glutamine and arginine; subsequently, hydrolyzed collagen was provided. Thirty-six days after the development of the pressure ulcer, it has recovered. After four months, the patient was discharged. The nutritional intervention was crucial in the recovery of UPP. The need to prevent this type of ulcers through timely and adequate monitoring is emphasized.


Subject(s)
Humans , Male , Adult , Nutritional Support/methods , Pressure Ulcer/diet therapy , Malnutrition/therapy , Sacrococcygeal Region , Nutrition Rehabilitation , Nutritional Support/standards , Pressure Ulcer/pathology , Malnutrition/etiology , Malnutrition/metabolism
5.
Biomedical and Environmental Sciences ; (12): 337-347, 2021.
Article in English | WPRIM | ID: wpr-878369

ABSTRACT

Objective@#Nutrition is closely related to the health of the elderly population. This study aimed to provide a comprehensive picture of the nutrition status of elderly Chinese and its related dietary, geographical, and socioeconomic factors.@*Methods@#A total of 13,987 ≥ 60-year-old persons from the 2010-2013 Chinese National Nutrition and Health Survey were included to evaluate various aspects of malnutrition, including underweight, overweight or obesity, and micronutrient inadequacy.@*Results@#Overall, the prevalence of obesity, overweight, and underweight was 12.4%, 34.8%, and 5.7%, respectively, with disparities both geographically and socioeconomically. The prevalence of underweight was higher among the older old (≥ 75 years), rural residents and those with low income, with low education status, and residing in undeveloped West areas. More than 75% of the elderly do not meet the Dietary Reference Intakes for vitamins A, B @*Conclusions@#Obesity epidemic, inadequacy of micronutrient intake, and high prevalence of underweight and anemia in susceptible older people are the major nutrition challenges for the rapidly aging population in China.


Subject(s)
Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Age Factors , China/epidemiology , Cross-Sectional Studies , Diet/statistics & numerical data , Health Surveys , Malnutrition/etiology , Micronutrients/deficiency , Nutritional Status , Overweight/etiology , Risk Factors , Socioeconomic Factors , Thinness/etiology
6.
Rev. Col. Bras. Cir ; 48: e20202666, 2021. tab
Article in English | LILACS | ID: biblio-1155359

ABSTRACT

ABSTRACT Introduction: bariatric surgery is currently the only treatment that leads to long-term and sustained weight loss and decreased morbidity and mortality in morbidly obese individuals. Roux-en-Y bypass causes weight loss by restricting food intake associated with reduced intestinal absorption, in addition to multiple endocrine and satiogenic effects. Biliopancreatic diversion promotes weight loss mainly due to poor absorption of the nutrients ingested. Both procedures exclude parts of the gastrointestinal tract. Objective: to describe four cases of revisional surgery after primary bariatric surgery, due to serious nutritional complications, and to review the literature regarding this subject. Methods: a retrospective analysis of patients of Unicamps bariatric center database and review of the literatures were performed. Results: four patients were identified, 2 women and 2 men, with a mean age of 48 years. The mean body mass index before revisional surgery was 23.7 kg/m2. Three patients underwent Scopinaro biliopancreatic diversion, and onde patient underwent Roux-en-Y gastric bypass. The revisional surgeries were revision, conversion, and reversion. One patient died. For the review of the literature 12 articles remained (11 case reports and 1 case series). Another five important original articles were included. Conclusion: fortunately, revision surgery is rarely necessary, but when indicated it has increased morbidity, It can be revision, reverion or conversion according to the severity of the patient and the primary surgery performed.


RESUMO Introdução: atualmente, a cirurgia bariátrica é o único tratamento que leva à perda de peso prolongada e sustentada e diminuição da morbimortalidade em indivíduos obesos mórbidos. O bypass em Y-de-Roux causa perda de peso restringindo a ingestão de alimentos associada à redução da absorção intestinal, além de múltiplos efeitos endócrinos e sacietógenos. O desvio biliopancreático promove a perda de peso principalmente devido à diminuição da absorção dos nutrientes ingeridos. Ambos os procedimentos excluem partes do trato gastrointestinal. Objetivo: descrever 4 casos de cirurgia revisional após cirurgia bariátrica primária, devido a graves complicações nutricionais, bem como realizar uma revisão da literatura sobre esse assunto. Métodos: foi realizada uma análise retrospectiva dos pacientes do banco de dados do serviço de cirurgia bariátrica da Unicamp e revisão da literatura. Resultados: foram identificados 4 pacientes, 2 mulheres e 2 homens, com média de idade de 48 anos, o IMC antes da cirurgia revisional eram em média 23,7. Os pacientes haviam sido submetidos em 3 casos a cirurgia de Scopinaro e 1 caso ao bypass gástrico em Y-de-Roux. As cirurgias revisionais foram de revisão, conversão e reversão. Um paciente evoluiu a óbito. Em relação a revisão da literatura, foram selecionados 12 artigos (11 relatos de casos e 1 série de casos). Outros cinco artigos originais importantes foram incluídos. Conclusão: felizmente, a cirurgia revisional raramente é necessária, mas, quando indicada, apresenta alta morbidade. São cirurgias de revisão, reversão ou conversão, de acordo com a gravidade do paciente e a cirurgia primária realizada.


Subject(s)
Humans , Male , Female , Postoperative Complications/surgery , Reoperation , Obesity, Morbid/surgery , Malnutrition/etiology , Bariatric Surgery/adverse effects , Bariatric Surgery/methods , Postoperative Complications/etiology , Gastric Bypass , Retrospective Studies , Treatment Outcome , Laparoscopy , Middle Aged
7.
Rev. bras. geriatr. gerontol. (Online) ; 24(2): e200339, 2021. tab
Article in English, Portuguese | LILACS | ID: biblio-1288544

ABSTRACT

Resumo Objetivo Investigar o comprometimento do apetite em pessoas idosas hospitalizadas com câncer e sua associação com estado nutricional e presença de caquexia. Métodos Estudo transversal realizado com pessoas idosas de ambos os sexos, diagnosticadas com neoplasia maligna, de julho de 2017 a março de 2019 em um hospital universitário. A amostra final foi composta por 90 pacientes. O comprometimento do apetite foi identificado pelo Questionário de Apetite e Sintomas para Pacientes com Câncer (CASQ) e o estado nutricional pela Avaliação Subjetiva Global Produzida pelo Próprio Paciente (ASG-PPP). A presença de caquexia foi avaliada pela perda de peso >5% nos últimos 6 meses; ou índice de massa corporal (IMC) <20 kg/m2 e perda de peso >2%; ou índice de músculo esquelético apendicular consistente com sarcopenia e perda de peso >2%. Resultados Houve predomínio de indivíduos do sexo masculino (56,7%), autodeclarados não brancos (56,7%), com tumores localizados no trato gastrointestinal (75,6%) e mediana de idade de 67 anos. 75,6% dos indivíduos apresentaram comprometimento do apetite, 57,8% suspeita de desnutrição ou desnutrição de algum grau, 54,4% caquexia e 92,2% necessidade de intervenção nutricional. Houve associação entre as categorias do CASQ com estado nutricional (p=0,001) e presença de caquexia (p=0,050). Após análise de regressão logística, a desnutrição permaneceu associada ao comprometimento do apetite [OR: 4,68 (IC 95%: 1,50-14,56), p=0,008]. Conclusão A presença de desnutrição aumentou as chances de comprometimento do apetite, o que reforça a necessidade da triagem e intervenção nutricional precoces, a fim de reduzir e/ou evitar os agravos nutricionais.


Abstract Objective To investigate appetite impairment in older adults hospitalized with cancer and its association with nutritional status and cachexia. Method A cross-sectional study, conducted with older adults men and women diagnosed with malignant neoplasia from July 2017 to March 2019 at a university hospital. The final sample consisted of 90 patients. Appetite was evaluated using the Cancer Appetite and Symptom Questionnaire (CASQ) and nutritional status was determined using the Patient-Generated Subjective Global Assessment (PG-SGA). Presence of cachexia was assessed by weight loss >5% in the last 6 months; or body mass index (BMI) <20 kg/m2 and weight loss >2%; or appendicular skeletal muscle index consistent with sarcopenia and weight loss >2%. Results There was a predominance of male (56.7%) self-declared non-white individuals (56.7%), with tumors in the gastrointestinal tract (75.6%) and median age of 67.0 years. 75.6% of the individuals have impaired appetite, 57.8% suspected malnutrition or malnutrition of some degree, 54.4% cachexia and 92.2% needed nutritional intervention. There was significant association between CASQ categories with nutritional status (p= 0.001) and presence of cachexia (p=0.050). After logistic regression analysis, malnutrition remained associated with impaired appetite assessed by CASQ score [OR: 4.68 (CI 95%: 1.50-14.56), p=0.008] Conclusion The presence of malnutrition increased the chances of appetite impairment, which reinforces the need for early nutritional screening and intervention, in order to reduce and/or avoid nutritional problems.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Appetite , Cachexia/etiology , Nutritional Status , Malnutrition/etiology , Neoplasms/complications , Cross-Sectional Studies
8.
Ciênc. Saúde Colet. (Impr.) ; 25(12): 5003-5016, Dec. 2020. tab
Article in Portuguese | LILACS, ColecionaSUS, SES-SP | ID: biblio-1142701

ABSTRACT

Resumo A infecção pelo HIV é preditora de diversas alterações metabólicas e de composição corporal, além de quadro de desnutrição, anemia e hipovitaminoses. Existem assim, especificidades de diagnóstico e tratamento conforme o estágio da doença e o ambiente ambulatorial ou hospitalar. O objetivo desse trabalho é apresentar arcabouço teórico e conceitual sobre a realização do diagnóstico nutricional em pessoas que vivem com HIV/AIDS. Buscou-se evidências científicas atuais nacionais e internacionais publicadas em artigos científicos, livros recentes, protocolos, consensos e diretrizes. O diagnóstico nutricional engloba vários aspectos e habilidades clínicas e conhecimentos específicos sobre essa morbidade. Assim, devido sua complexidade e abrangência, compreende: história clínica e situação clínica atual, consumo alimentar, dados antropométricos, composição corporal, bioquímicos, pressão arterial e exame físico. Foi demonstrado o processo de diagnóstico nutricional de forma a fornecer subsídios para as equipes de saúde na identificação de parâmetros que possibilitem instituir um plano de cuidado nutricional que promova, previna e recupere as alterações detectadas nas pessoas que vivem com HIV/AIDS.


Abstract HIV infection is a predictor of several metabolic and body composition alterations, in addition to malnutrition, anemia, and hypovitaminosis. There are thus specificities of diagnosis and treatment depending on the stage of the disease and the outpatient or hospital environment. The scope of this narrative review was to update the conceptual and theoretical framework regarding the nutritional diagnosis of people living with HIV/AIDS. Current national and international scientific evidence published in scientific articles, recent books, protocols, consensuses, and guidelines were analyzed. The nutritional diagnosis encompasses several clinical aspects and abilities and specific knowledge about HIV/AIDS, such as: clinical history and current clinical situation, food consumption, anthropometric data, body composition, and biochemistry, blood pressure and physical examination. The nutritional diagnosis process was demonstrated in order to provide subsidies for the health teams in the identification of parameters that make it possible to establish a plan for nutritional care to promote, prevent and recuperate the alterations detected in people living with HIV/AIDS.


Subject(s)
Humans , HIV Infections/diagnosis , Acquired Immunodeficiency Syndrome/diagnosis , Malnutrition/diagnosis , Malnutrition/etiology , Malnutrition/epidemiology , Body Composition , Review Literature as Topic
9.
Arq. gastroenterol ; 57(4): 375-380, Oct.-Dec. 2020. tab
Article in English | LILACS | ID: biblio-1142350

ABSTRACT

ABSTRACT BACKGROUND: The protein-energy malnutrition alters the prognosis of patients with cirrhosis. Its prevalence may vary according to the etiology of liver disease, it´s severity and the evaluation of the method applied. The infection by the hepatitis C virus (HCV) and alcoholism are the main etiologies of cirrhosis and result in a significant morbidity and mortality. OBJECTIVE: To evaluate the nutritional status of patients with cirrhosis according the liver disease etiology and severity. METHODS: It is a prospective study, in which the sample was for convenience and consisted of patients with cirrhosis, infected by HCV or alcoholic etiology. The nutritional status evaluation was carried out through anthropometry, food consumption, bioelectrical impedance (BIA) and subjective global assessment (SGA). The anthropometric data evaluated were weight, height, body mass index (BMI), triceps skinfold (TSF), circumference of the arm (CA), non-dominant handshake strength (FAM) and the adductor pollicis muscle thickness (APM). Patients were classified according to the severity of liver disease, using the Child-Pugh and Model for End-stage Liver Diseases (MELD) scores. RESULTS: Ninety patients with cirrhosis were evaluated, 47 with HCV and 43 with alcoholic etiology. The prevalence of protein-calorie malnutrition ranged from 10.9% to 54.3% in the HCV group and from 4.7% to 20.9% in the alcoholic group, depending on the method used for evaluation. The group with HCV infection presented a higher malnutrition prevalence in comparison to the alcoholic in the following evaluations: TSF (P<0.001), phase angle (PA) (P=0.016) and SGA (P=0.010). PA values were lower in patients with viral cirrhosis (5.68±1.05) when compared to those with alcoholic etiology (6.61±2.31) (P=0.016). When all patients were analyzed, regardless of etiology, an inversely correlation was observed among Child-Pugh score and PA values (P=0.018). CONCLUSION: HCV cirrhosis showed worse nutritional parameters in comparison to alcoholic etiology; however, the PA was associated with worse liver function in both etiologies.


RESUMO CONTEXTO: A desnutrição proteico-calórica altera o prognóstico dos pacientes com cirrose. Sua prevalência pode variar de acordo com a etiologia da hepatopatia, gravidade da doença e o método de avaliação empregado. A infeção pelo vírus da hepatite C (VHC) e o alcoolismo, estão entre as principais etiologias da cirrose e acarretam significativa morbidade e mortalidade. OBJETIVO: Avaliar o estado nutricional do paciente com cirrose de acordo com a etiologia e gravidade da hepatopatia. MÉTODOS: Estudo prospectivo, em que a amostra foi por conveniência constituída de pacientes com cirrose, infectados pelo vírus da hepatite C (VHC) ou etiologia alcoólica. A avaliação do estado nutricional foi realizada através da antropometria, consumo alimentar, bioimpedância elétrica (BIA) e da avaliação subjetiva global (ASG). Os dados antropométricos avaliados foram: peso, altura, índice de massa corporal (IMC), prega cutânea triciptal (PCT), circunferências do braço (CB), força do aperto de mão não dominante (FAM) e a espessura do músculo adutor do polegar (MAP). Os pacientes foram classificados de acordo com a gravidade da hepatopatia, através do escore Child-Pugh e Model for End-stage Liver Diseases (MELD). RESULTADOS: Foram avaliados 90 pacientes com cirrose, 47 com etiologia pelo VHC e 43 com etiologia alcoólica. A prevalência de desnutrição proteico-calórica variou de 10,9% a 54,3% no grupo do VHC e de 4,7% a 20,9% no grupo dos alcoolistas, dependendo do método utilizado para avaliação. O grupo com infecção pelo VHC apresentou maior prevalência de desnutrição em relação ao de etiologia alcoólica nas seguintes avaliações: PCT (P<0,001), ângulo de fase (AF) (P=0,016) e ASG (P=0,010). Os valores do AF foram menores nos pacientes com cirrose viral (5,68±1,05) quando comparados aos com etiologia alcoólica (6,61±2,31) (P=0,016). Quando analisados todos os pacientes, independente da etiologia da hepatopatia, observou-se uma correlação inversamente proporcional entre a classificação de Child-Pugh e os valores de AF (P=0,018). CONCLUSÃO: A cirrose pelo VHC demonstrou piores parâmetros nutricionais em relação à etiologia alcoólica; entretanto, em ambas etiologias o AF foi associado com pior função hepática em ambas etiologias.


Subject(s)
Humans , Protein-Energy Malnutrition/epidemiology , Malnutrition/etiology , Liver Cirrhosis/complications , Nutrition Assessment , Nutritional Status , Prospective Studies , Carcinoma, Hepatocellular , Liver Neoplasms
10.
J. bras. nefrol ; 42(4): 429-436, Oct.-Dec. 2020. tab
Article in English, Portuguese | LILACS | ID: biblio-1154637

ABSTRACT

Abstract Indroduction: Establishing which parameters to use for diagnosing malnutrition in hemodialysis patients is a challenge in clinical practice. The handgrip strength (HGS) has stood out as a method of assessing nutritional status. Thus, the aim of this study was to determine the cut-off point for HGS in the assessment of the risk of malnutrition and inflammation in HD patients, and its association with other parameters. Methods: Study carried out in hemodialysis units in the city of Curitiba, Brazil. We obtained the cut-off point of the HGS through the ROC curve, using the malnutrition and inflammation score (MIS) as a reference. We checked the relationship (Odds ratio) between the variables "MIS" and "HGS" with the other study variables using the multivariate analysis (logistic regression). Results: We assessed 238 patients (132 men), between 18 and 87 years of age (median = 59). The HGS cut-off point for diagnosing malnutrition and inflammation according to the reference used was <14.5 kg for women, and <23.5 kg for men. According to the HGS criteria, malnourished patients were older (OR = 0.958), with lower arm circumference (OR = 1.328) and higher scores in the malnutrition and inflammation score (OR = 0.85). Conclusion: HGS was significantly correlated with other nutritional assessment parameters. These results suggest that HGS is a valid screening tool to identify the risk of malnutrition and inflammation in hemodialysis patients.


Resumo Introdução: Estabelecer quais parâmetros utilizar para diagnóstico de desnutrição em pacientes em hemodiálise (HD) é um desafio na prática clínica. A força de preensão manual (FPM) tem-se destacado como um método de avaliação do estado nutricional. Assim, o objetivo deste estudo foi determinar o ponto de corte da FPM na avaliação do risco de desnutrição e inflamação de pacientes em HD e sua associação com outros parâmetros. Métodos: Estudo realizado em unidades de hemodiálise na cidade de Curitiba, Brasil. Ponto de corte da força de preensão manual obtido através da curva ROC, usando como referência o escore de desnutrição e inflamação (MIS). A relação (Odds ratio) entre as variáveis "MIS" e "FPM" com as demais variáveis do estudo foi verificada por meio de análise multivariada (regressão logística). Resultados: Foram avaliados 238 pacientes (132 homens), entre 18 e 87 anos (mediana = 59). Ponto de corte da FPM para diagnóstico de desnutrição e inflamação de acordo com a referência utilizada: < 14,5 kg para mulheres e < 23,5 kg para homens. Pacientes desnutridos conforme critérios da FPM eram mais velhos (OR=0,958), com menor circunferência do braço (OR=1,328) e maior pontuação no MIS (OR=0,85). Conclusão: A FPM foi correlacionada de forma significativa com outros parâmetros de avaliação nutricional. Esses resultados sugerem que a FPM é um instrumento de triagem válido para identificar risco de desnutrição e inflamação em pacientes em hemodiálise.


Subject(s)
Humans , Male , Female , Hand Strength , Malnutrition/diagnosis , Malnutrition/etiology , Nutrition Assessment , Nutritional Status , Renal Dialysis , Inflammation
11.
Buenos Aires; s.n; oct. 2020. 19 p. tab, graf, mapas.
Non-conventional in Spanish | UNISALUD, BINACIS, InstitutionalDB, LILACS | ID: biblio-1284008

ABSTRACT

La malnutrición por exceso es uno de los problemas de salud más prevalentes en niños y niñas en edad escolar, etapa en la que se observa un marcado incremento en el sobrepeso y la obesidad. Se describe el estado nutricional de una cohorte de niños y niñas que concurrieron a escuelas de gestión estatal de CABA, evaluados/as en 1º y 6º grado, se comparan las prevalencias de sobrepeso / obesidad y su asociación con sexo, zona de la ciudad, tipo de jornada escolar y realización de intervenciones educativas por parte del Programa Mi Escuela Saludable, y se analiza la incidencia del exceso de peso y, en particular, de la obesidad y su asociación con las variables mencionadas.


Subject(s)
Humans , Male , Female , Child , School Health Services , Health Programs and Plans , Food and Nutrition Education , Malnutrition/diagnosis , Malnutrition/etiology , Malnutrition/prevention & control , Malnutrition/epidemiology , Overweight/diagnosis , Overweight/epidemiology , Pediatric Obesity/diagnosis , Pediatric Obesity/prevention & control , Pediatric Obesity/epidemiology
12.
Rev. bras. ciênc. saúde ; 24(3): 465-474, set. 25, 2020. tab
Article in Portuguese | LILACS, ColecionaSUS, CONASS, SES-MA | ID: biblio-1179431

ABSTRACT

Objetivo: Avaliar o perfil nutricional de pacientes onco-hematológicos internados em um hospital especializado em câncer em São Luís - MA. Metodologia: Estudo transversal, retrospectivo, analítico, com coleta de dados secundária, envolvendo pacientes com idade mínima de 18 anos, de ambos os gêneros e que tenham sido submetidos a pelo menos uma ASG-PPP (Avaliação Subjetiva Global Produzida Pelo Paciente). Os dados foram coletados em registros do Serviço de Nutrição e Dietética do hospital. Analisaram-se dados demográficos (gênero e idade), clínicos (diagnóstico) e nutricionais: Índice de massa corporal (IMC), circunferên-cia braquial (CB), prega cutânea tricipital (PCT), circunferência muscular do braço (CMB) e ASG-PPP. As análises foram realizadas no programa estatístico Stata® 13.0. O nível de significância utilizado para os testes foi de p<0,05. Resultados: Foram avaliados 330 pacientes, onde foi constatado que 67,58% eram de adultos e 32,42% de idosos, com maior frequência do sexo masculino, com 60,30%. Ocorreu maior incidência de leucemia (58,48%), seguidos de linfomas (24,85%), mieloma múltiplo (13,33%) e síndrome mielodisplásica (3,3%). Na avaliação do estado nutricional os resultados mostraram que a ASG-PPP detectou maior número de pacientes com algum grau de desnutrição do que outros indicadores (93,94%), seguido pela PCT (65,76%), CMB (53,64%), CB (45,45%) e IMC (14,87%). De acordo com o IMC, foi encontrado maior incidência de eutrofia, correspondendo a 57,27% da amostra. Conclu-são: Diante do que foi encontrado, destaca-se que a desnutrição é um aspecto de extrema importância a ser considerado no tratamento de pacientes onco-hematológicos, visto que pode interferir diretamente no prognóstico da doença. (AU)


Objective: To evaluate the nutritional profile of onco-hematological patients admitted to a specialized cancer hospital in São Luís - MA. Methodology: Cross-sectional, retrospective, analytical study, with secondary data collection, involving patients aged at least 18 years, of both genders and having undergone at least one ASG-PPP (Subjective Global Assessment Produced by the Patient). Data were collected from records of the Hospital's Nutrition and Dietetics Service. Demographic (gender and age), clinical (diagnostic) and nutritional: Body Mass Index (BMI), Brachial Circumference (CB), Tricipital Skinfold (PCT), Muscular Arm Circumference (CMB) and ASG-PPP data were analyzed. The analyses were performed using the Stata® 13.0 statistical program. The level of significance used for the tests was p<0.05. Results: 330 patients were evaluated, in which it was found that 67.58% are adults and 32.42% are elderly, with a higher frequency of males with 60.30%. There was a higher incidence of Leukemia (58.48%), followed by Lymphomas (24.85%), Multiple Myeloma (13.33%) and Myelodysplastic Syndrome (3.3%). In the assessment of nutritional status, the results showed that ASG-PPP detected a greater number of patients with some degree of malnutrition than other indicators (93.94%), followed by PCT (65.76%), CMB (53.64%), CB (45.45%) and BMI (14.87%). According to the BMI, a higher incidence of eutrophy was found, which corresponds to 57.27% of the sample. Conclusion: In view of what was found, it is highlighted that malnutrition is an extremely important aspect to be considered in the treatment of onco-hematological patients, since it can directly interfere in the prognosis of the disease. (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Myelodysplastic Syndromes/complications , Leukemia/complications , Nutritional Status , Malnutrition/etiology , Lymphoma/complications , Cross-Sectional Studies , Retrospective Studies
14.
Article in English | LILACS, SES-SP | ID: biblio-1136706

ABSTRACT

ABSTRACT Objective: To correlate the nutritional status with variables associated to the type of diet and feeding route of children and adolescents with spastic quadriplegic cerebral palsy (CP). Methods: This cross-sectional study included 28 patients aged ≤13 years old who presented a diagnosis of spastic quadriplegic CP and were followed by the nutrition team of the Outpatient Clinic for Special Patients of Hospital de Clínicas de Uberlândia - Universidade Federal de Uberlândia (HC-UFU), between July/2016 and January/2017. Consent forms were signed by the legal guardians. The nutritional status was evaluated and data on dietary complications food route and type of diet were collected. For the description of data, average and median values were used. Correlation was tested with Spearman's index. Significance was set at p<0.05. Results: 75% of patients used alternative feeding routes (nasoenteral, catheter or gastrostomy), 57% were eutrophic. The most frequent complications were oropharyngeal dysphagia, reflux and intestinal constipation. No correlation was found between the occurrence of complications and the nutritional status. There was a positive correlation between the diet received and the patient's nutritional status (0.48; p=0.01), i.e. individuals with adequate caloric and macronutrients intake had a better nutritional status. Conclusions: The results reinforce the need for continued nutritional guidance for the children's parents/caregivers, as well as the choice of an adequate rout of feeding to each child by the multi-professional team, in order to contribute to improved nutritional status and adequate dietary intake.


RESUMO Objetivo: Correlacionar o estado nutricional com variáveis associadas ao tipo de dieta e via de alimentação de crianças e adolescentes com paralisia cerebral (PC) tetraparética espástica. Métodos: Estudo de corte transversal com 28 pacientes com idade ≤13 anos, atendidos pela equipe de nutrição do Ambulatório de Pacientes Especiais do Hospital de Clínicas de Uberlândia da Universidade Federal de Uberlândia (HC-UFU), entre julho de 2016 e janeiro de 2017, que apresentavam diagnóstico de PC tetraparética espástica. Os pacientes incluídos tiveram o termo de consentimento assinado pelo responsável legal. Avaliou-se o estado nutricional e coletaram-se dados sobre complicações alimentares, via de alimentação e tipo de dieta. Para descrição desses dados, foram utilizadas média e mediana; para análises de correlação, correlação de Spearman, sendo significante p<0,05. Resultados: Neste estudo, 75% dos pacientes utilizavam via alternativa para alimentação (sonda nasoenteral ou gastrostomia) e 57% eram eutróficos. As complicações mais frequentes foram disfagia orofaríngea, refluxo e obstipação intestinal. Não houve correlação entre ocorrência de complicações e estado nutricional. Observou-se correlação positiva entre dieta recebida e estado nutricional dos pacientes (0,48; p=0,01), sendo que indivíduos com adequada ingestão calórica e de macronutrientes apresentaram melhor classificação do estado nutricional. Conclusões: Os resultados obtidos reforçam a necessidade de orientações nutricionais contínuas para os pais/cuidadores das crianças do estudo, bem como a escolha de uma via de alimentação adequada a cada uma delas pela equipe multiprofissional, a fim de contribuir para a melhora do estado nutricional e da ingestão alimentar.


Subject(s)
Energy Intake , Cerebral Palsy/complications , Nutritional Status , Parents/education , Severity of Illness Index , Cross-Sectional Studies , Enteral Nutrition/adverse effects , Malnutrition/etiology , Feeding Behavior
15.
ABCD (São Paulo, Impr.) ; 33(3): e1537, 2020. tab
Article in English | LILACS | ID: biblio-1141901

ABSTRACT

ABSTRACT Background: Esophageal atresia is congenital anomaly with high mortality. Surgical complications and changes in nutritional status are common problems after surgical correction. Aim: To evaluate nutritional status, esophageal stenosis, and respiratory complications among children who had repaired esophageal atresia. Methods: Children aged >2 months old with repaired esophageal atresia were included in the current study. Gender, age, weight, and height were recorded for each case. Height for age and weight for age were calculated for each case. Results: According to weight for length percentile, 41.02% of the cases were underweight. Esophageal stenosis was seen in 54.76% of the obtained esophagograms. Conclusion: Underweight was present in 41.02 of the patients according to weight-for-height percentile.


RESUMO Racional: Atresia de esôfago é anomalia congênita com mortalidade alta. Complicações cirúrgicas e alterações no estado nutricional são problemas comuns após correção cirúrgica. Objetivo: Avaliar o estado nutricional, a estenose esofágica e as complicações respiratórias em crianças que tiveram a reparação de atresia de esôfago. Métodos: Crianças com idade> 2 meses de idade com atresia esofágica reparada foram incluídas no estudo atual. Sexo, idade, peso e altura foram registrados para cada caso. A altura por idade e o peso por idade foram calculados para cada caso. Resultados: De acordo com o peso para o percentil de comprimento, 41,02% dos casos estavam abaixo do peso. Estenose esofágica foi observada em 54,76% do esofagograma obtido. Conclusão: O baixo peso esteve presente em 41,02 dos pacientes, de acordo com o percentil peso/estatura.


Subject(s)
Humans , Infant , Malnutrition/etiology , Malnutrition/epidemiology , Esophageal Atresia/surgery , Esophageal Atresia/complications , Esophageal Stenosis/etiology , Esophageal Stenosis/epidemiology , Body Weight , Incidence
16.
ABCD (São Paulo, Impr.) ; 33(1): e1486, 2020. tab
Article in English | LILACS | ID: biblio-1130507

ABSTRACT

ABSTRACT Background: Esophageal atresia is congenital anomaly with high mortality. Surgical complications and changes in nutritional status are common problems after surgical correction. Aim: T o evaluate nutritional status, esophageal stenosis, and respiratory complications among children who had repaired esophageal atresia. Methods: Children aged >2 months old with repaired esophageal atresia were included in the current study. Gender, age, weight, and height were recorded for each case. Height for age and weight for age were calculated for each case. Results: According to weight for length percentile, 41.02% of the cases were underweight. Esophageal stenosis was seen in 54.76% of the obtained esophagograms. Conclusion: Underweight was present in 41.02 of the patients according to weight-for-height percentile.


RESUMO Racional: Atresia de esôfago é anomalia congênita com mortalidade alta. Complicações cirúrgicas e alterações no estado nutricional são problemas comuns após correção cirúrgica. Objetivo: Avaliar o estado nutricional, a estenose esofágica e as complicações respiratórias em crianças que tiveram a reparação de atresia de esôfago. Métodos: Crianças com idade> 2 meses de idade com atresia esofágica reparada foram incluídas no estudo atual. Sexo, idade, peso e altura foram registrados para cada caso. A altura por idade e o peso por idade foram calculados para cada caso. Resultados: De acordo com o peso para o percentil de comprimento, 41,02% dos casos estavam abaixo do peso. Estenose esofágica foi observada em 54,76% do esofagograma obtido. Conclusão: O baixo peso esteve presente em 41,02 dos pacientes, de acordo com o percentil peso/estatura.


Subject(s)
Humans , Infant , Malnutrition/etiology , Malnutrition/epidemiology , Esophageal Atresia/surgery , Esophageal Atresia/complications , Esophageal Stenosis/etiology , Esophageal Stenosis/epidemiology , Body Weight , Incidence
17.
Rev. medica electron ; 41(5): 1166-1177, sept.-oct. 2019. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1094120

ABSTRACT

RESUMEN Introducción: la nutrición tiene importancia capital en la evolución de los pacientes ingresados. La prevalencia de malnutrición oscila entre 30% y 60% de los enfermos hospitalizados. Objetivo: evaluar impacto en la mortalidad y complicaciones a corto plazo de una intervención nutricional precoz. Material y método: se realizó un estudio caso control con todos los pacientes que ingresaron en la Unidad de Cuidados intensivos emergentes con el diagnóstico de neumonía adquirida en la comunidad asociada a desnutrición en Hospital Militar Dr. Carlos J. Finlay, de noviembre de 2017 hasta mayo del 2018. Resultados: la media de la edad del estudio fue de 80,73 ± 9,01 años. El 46 % fueron mujeres. La mortalidad global estuvo en el 26 %. El 69 % de los pacientes presento alguna complicación. Existió una mayor sobrevida en el grupo de estudio (7 fallecidos y 29 vivos), que en el grupo de control donde hubo 12 fallecidos y 24 vivos x2 = 0,18. En la tabla 2 se evidencia que existe diferencia entre los grupos según las complicaciones aparecidas. Fue marcada la diferencia entre los grupos en relación a la cantidad de pacientes con diarreas. La incidencia fue mayor tanto en el subgrupo de vivos(8) como en el de fallecidos(3) del grupo control. Por otro lado la hiperglucemia fue mucho mayor en el grupo de estudio(11) y sin embargo, no hubo impacto en la mortalidad x2 = 0,03. En la tabla 3 se evidencia una fuerte evidencia que relaciona al estado nutricional deficiente con una peor evolución. Entre los fallecidos solo 1 tenía un estado nutricional catalogado como desnutrido ligero, sin embargo entre los 22 fallecidos 14 presentaron desnutrición severa. Conclusiones: el estado nutricional al ingreso impacta negativamente en la mortalidad a corto plazo y la estrategia nutricional mixta precoz no reduce ese aspecto sin embargo si reduce el número de complicaciones aunque se asoció a mayor incidencia de hiperglucemia sin impactar en la mortalidad (AU).


SUMMARY Introduction: nutrition has a capital importance in the evolution of in-patients. Malnutrition prevalence ranges from 30 % to 60 % of the admitted patients. Objective: to evaluate the impact on mortality and the short time complications of the precocious nutritional intervention. Material and Method: a case control study was carried out with all patients who entered the Emergency Intensive Care Unit with the diagnosis of community-acquired pneumonia associated to malnutrition in the Military Hospital "Dr, Carlos J. Finlay" from November 2017 to May 2018. Results: the average age was 80.73 ± 9.01 years. 46 % were female patients. Global mortality was 26 %. 69 % of patients had complications. The group of study showed a higher survival (7 deads and 29 survivors) than the control one where there were 12 deads and 24 survivors (2=0.18). Table 2 shows that there are differences between groups according to the complications found. The difference between groups was remarkable in relation to the quantity of patients with diarrhea. The incidence was higher both in the group of survivors(8) and in the group of dead peoples(3) of the control group. On the other hand, hyperglycemia was much higher in the group of study(11) but without striking on mortality (2= 0.03). Table 3 shows strong evidence relating deficient nutritional status to a worth evolution. Among the deceased patients only 1 had a nutritional status classified as slightly malnutrition, but among the 22 deceased, 14 had severe malnutrition. Conclusions: the nutritional status at admission negatively strikes on short term mortality, and mixed precocious nutritional strategy does not reduce that aspect. However it does reduce the number of complications, though it was associated to a higher incidence of hyperglycemia without striking on mortality (AU).


Subject(s)
Humans , Aged , Pneumonia/complications , Malnutrition/diagnosis , Early Medical Intervention , Pneumonia/mortality , Nutrition Programs , Malnutrition/etiology , Malnutrition/mortality , Malnutrition/therapy
18.
Gac. méd. Méx ; 155(3): 229-235, may.-jun. 2019. tab, graf
Article in English, Spanish | LILACS | ID: biblio-1286496

ABSTRACT

Resumen Introducción: La bioimpedancia eléctrica multifrecuencia (BIE) evalúa con precisión la composición corporal. Objetivo: Investigar el estado nutricional y su relación con el índice de masa corporal (IMC) o el ángulo fase obtenido por BIE en pacientes con enfermedad renal terminal (ERT) en hemodiálisis. Método: En 99 pacientes en hemodiálisis (43.6 ± 17.2 años, 58.8 % varones) se evaluó IMC, BIE y puntuación de desnutrición (DMS, Dialysis Malnutrition Score). La independencia de las asociaciones del IMC y el ángulo fase con el DMS se determinó con regresión lineal múltiple. Resultados: El riesgo de desnutrición (DMS > 13) se incrementó gradualmente entre los sujetos con IMC y ángulo fase normales (44.4 %), IMC bajo (45.8 %), ángulo fase bajo (64.0 %) y en aquellos con ambos parámetros anormales (68.0 %). El ángulo fase fue la única variable asociada independientemente con el estado nutricional de los pacientes (coeficiente beta estandarizado −0.372, p < 0.001), lo que explicó 13.8 % de la variación en el DMS. Conclusiones: El ángulo fase se asocia inversa e independientemente con el riesgo de desnutrición en pacientes con ERT, lo que sugiere que la composición corporal evaluada por BIE pudiera ser mejor que el IMC en la valoración clínica de pacientes con esta enfermedad.


Abstract Introduction: Multi-frequency bio-impedance analysis (BIA) accurately evaluates body composition. Objective: To assess nutritional status and its relationship with body mass index (BMI) or with BIA-obtained phase angle in patients with end-stage renal disease (ESRD) on hemodialysis. Method: BMI, BIA and dialysis malnutrition score (DMS) were assessed in 99 patients on hemodialysis (43.6 ± 17.2 years of age, 58.8% males). Multivariate linear regression analysis was used to determine BMI and phase angle independent associations with DMS. Results: Malnutrition risk (DMS > 13) showed a gradual increase among patients with normal BMI and phase angle (44.4%), low BMI (45.8%), low phase angle (64.0%), and in those with both parameters at abnormal ranges (68.0%). The phase angle was the only variable that was independently associated with patient nutritional status (standardized coefficient beta −0.372, p < 0.001), accounting for 13.8% of DMS variation. Conclusion: Phase angle is inversely and independently associated with malnutrition risk in patients with ESRD, which suggests that BIA-assessed body composition might be better than BMI in the clinical assessment of patients with ESRD.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Young Adult , Renal Dialysis/methods , Electric Impedance , Malnutrition/epidemiology , Kidney Failure, Chronic/therapy , Body Composition , Body Mass Index , Nutritional Status , Cross-Sectional Studies , Malnutrition/diagnosis , Malnutrition/etiology
19.
Journal of Peking University(Health Sciences) ; (6): 510-518, 2019.
Article in Chinese | WPRIM | ID: wpr-941842

ABSTRACT

OBJECTIVE@#To investigate the relationship between malnutrition-inflammation-atherosclerosis (MIA) syndrome and deterioration of global and specific domains of cognitive function in peritoneal dialysis (PD) patients.@*METHODS@#This was a multi-center prospective cohort study. The PD patients who met the inclusion criteria were examined with general and specific cognitive function between March 2013 and November 2013. The patients were divided into MIA0, MIA1 and MIA2 groups, according to items of "Yes" for whether or not having cardiovascular disease, serum albumin≤35 g/L or high-sensitive C-reactive protein (hs-CRP) ≥3 mg/L. After 2 years, the patients maintained on PD would be repeatedly measured with cognitive function. The Chi-square test, One-way ANOVA, Kruskal-wallis H rank sum test were used to compare the differences of clinical characteristics, biochemical data, and global and specific cognitive function parameters among the three groups at baseline, and two years later, respectively. The Bonferroni method was applied to adjust the significance level for further comparison between each two different groups. The change of score in each cognitive parameter of global and specific domains was used as dependent variable. Age, gender, education level, depression index, body-mass index, diabetes mellitus, serum sodium levels and MIA (MIA0 was control, MIA1 and MIA2 as dummy variables) were all included in the multivariable linear regression models to analyze the risk factors of the deterioration of cognitive function. The analysis for each cognitive domain was adjusted for the baseline score of the corresponding cognitive parameter. All the analyses were performed using SPSS for Windows, software version 25.0 (SPSS Inc., Chicago, IL).@*RESULTS@#Over two-year follow up, the prevalence of cognitive impairment increased from 20.0% to 24.7%, absolute decrease of 3MS scores were more significantly decreased in MIA2 (-3.9±12.0 vs. 1.1±6.7, P<0.01) and MIA1 group (-2.3±11.8 vs. 1.1±6.7, P<0.05) than those in MIA0 group respectively. Specific cognitive functions, included executive function (trail-making tests A and B, P=0.401, P=0.176), immediate memory (P=0.437), delayed memory (P=0.104), visuospatial skill (P=0.496), and language ability (P=0.171) remained unchanged. Advanced age, lower education, diabetes mellitus and depression were all correlated with the deterioration of one or more cognitive domains, and the patients having one item of MIA syndrome were prone to develop the deterioration of 3MS (P=0.022). Furthermore, the patients having two or more items of MIA syndrome were more likely to develop the deterioration of not only 3MS (P <0.001), but also delayed memory, visuospatial skill, and language ability (P=0.002, P=0.007, P=0.004, respectively).@*CONCLUSION@#Patients with one item or above of MIA syndrome were at high-risk for the deterioration of global cognitive function. The more MIA syndrome items there were, the more specific cognitive domains deteriorated.


Subject(s)
Humans , C-Reactive Protein , Cardiovascular Diseases/etiology , Cognition , Cognitive Dysfunction/complications , Cross-Sectional Studies , Inflammation/etiology , Malnutrition/etiology , Peritoneal Dialysis , Prospective Studies
20.
Article in Portuguese | LILACS | ID: biblio-1046596

ABSTRACT

Introdução: O diagnóstico precoce do risco nutricional pode melhorar o prognóstico dos pacientes onco-hematológicos. Objetivo:Descrever o estado nutricional nos pacientes onco-hematológicos e avaliar os fatores associados ao risco nutricional nos pacientes onco-hematológicos de um hospital universitário terciário de Fortaleza - Ceará. Método: Estudo transversal que incluiu 127 pacientes adultos internados. Os dados de diagnóstico clínico e demográficos foram coletados por meio da análise de prontuários. O estado nutricional foi avaliado pelo índice de massa corporal (IMC), circunferência braquial (CB) e pela aplicação da ferramenta de triagem de risco nutricional - NRS-2002. Resultados: Pelos diferentes parâmetros, houve divergências no estado nutricional. A maioria da amostra apresentava risco nutricional de acordo com a avaliação da NRS-2002 (70,1%; n=89), seguida pela CB (33,9%; n=43) e pelo IMC (8,7%; n=11). Houve correlação positiva significativa entre IMC e idade [r=0,313, p<0,001] e CB [r=0,846, p<0,001], e associação significativa entre NRS-2002≥3 e IMC<18,5 kg/m² (p=0,023); NRS-2002 ≥3 e CB classificada como desnutrição (p=0,001); IMC<18,5kg/m² e CB classificada como desnutrição; e residir em zona urbana e apresentar CB adequada (p=0,023). Conclusão: Este estudo revelou alta prevalência de risco nutricional, bem como uma associação significativa entre risco nutricional e baixos valores de IMC e CB, e residir em zona rural. Assim, há a necessidade de utilizar uma combinação de indicadores, a fim de diagnosticar, de forma mais precisa e precoce, o estado nutricional desses pacientes.


Introduction: Early diagnosis of nutritional risk may improve the prognosis of oncohaematological patients. Objective: To describe the nutritional status and to evaluate the nutritional risk factors in oncohaematological patients of a tertiary university hospital in Fortaleza, Ceará. Method: This cross-sectional study included 127 patients hospitalized. Clinical and demographic diagnostic data were selected through chart analysis. The nutritional status was elaborated by body mass index (BMI), arm circumference (AC) and by the application of the nutritional risk screening (NRS-2002). Results:Due to the different parameters, there were differences in nutritional status. The majority of the presentation criteria were NRS-2002 70.1% (n=89), followed by the AC 33.9% (n=43) and the BMI 8.7% (n=11). There was a significant positive correlation between BMI and age [r=0.313, p<0.001] and AC [r=0.846, p<0.001]. There was a significant association between NRS-2002≥3 and BMI<18.5 kg/m² (p=0.023); NRS-2002≥3 and AC classified as malnutrition (p=0.001); BMI<18.5 kg/m² and AC classified as malnutrition; and reside in urban areas and present adequate AC (p=0.023). Conclusion: This study revealed a high prevalence of nutritional risk, as well as a significant association between nutritional risk and low BMI, AC and to reside in rural areas. Thus, there is a need to use a combination of indicators to diagnose the nutritional status of these patients in a more precise and early manner.


Introducción: El diagnóstico precoz del riesgo nutricional puede mejorar el pronóstico de los pacientes onco-hematológicos. Objetivo: Describir el estado nutricional en los pacientes onco-hematológicos y evaluar los factores asociados al riesgo nutricional en los pacientes onco-hematológicos de un Hospital Universitario Terciario de Fortaleza - Ceará. Método: Estudio transversal que incluyó a 127 pacientes adultos internados. Los datos de diagnóstico clínico y demográfico fueron recolectados a través de análisis de prontuarios. El estado nutricional fue evaluado por el índice de masa corporal (IMC), circunferencia braquial (CB) y por la aplicación de la herramienta de clasificación de riesgo nutricional - NRS-2002. Resultados: Diferentes parámetros, hubo divergencias en el estado nutricional. La mayoría de la muestra presentaba riesgo nutricional de acuerdo con la evaluación de la NRS-2002 70,1% (n=89), seguida por la CB 33,9% (n=43) y por IMC 8,7% (n=11). Se observó una correlación positiva significativa entre el IMC y la edad [r=0,313, p<0,001] y CB [r=0,846, p<0,001]. Se observó una asociación significativa NRS-2002≥3, e IMC<18,5 kg/m² (p=0,023) y CB desnutrida (p=0,001). Hubo asociación significativa entre IMC<18,5kg/m² y CB desnutrida (p=0,001), y entre residir en zona urbana y presentar CB adecuado (p=0,023). Conclusión: Alta prevalencia de riesgo nutricional, así como una asociación significativa entre riesgo nutricional y bajos valores de IMC y CB, y residir en zonas rurales. Hay la necesidad de utilizar una combinación de indicadores para diagnosticar de forma más precisa y precoz el estado nutricional de estos pacientes.


Subject(s)
Adult , Middle Aged , Aged , Aged, 80 and over , Nutrition Assessment , Nutritional Status , Hematologic Neoplasms/diet therapy , Mid-Upper Arm Circumference , Body Mass Index , Cross-Sectional Studies , Malnutrition/etiology
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